Saturday, April 12, 2014

Daily News: Reuters Health News Headlines - Diners in hepatitis A scare at suburban New York restaurant

Saturday, Apr 12, 2014 08:49 AM PDT

Diners in hepatitis A scare at suburban New York restaurant 
Saturday, Apr 12, 2014 08:49 AM PDT
Hundreds of diners at an Italian restaurant in suburban New York may have been exposed to hepatitis A in the last few weeks after a food handler there was found to have the liver disease, the county health department said. People who ate at or who were working at La Fontana restaurant in the village of Nyack, about 20 miles north of Manhattan, between March 19 and April 1 may have been exposed to the virus, the Rockland County health department said. The department is urging diners and employees who were at the restaurant between March 29 and April 1 who have not previously been vaccinated to obtain a free hepatitis A vaccination. The vaccination is only effective if taken within 14 days of exposure and so will be of no use to people who were at La Fontana earlier in March, the department said.
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Intercept's liver disease drug proves highly effective in study 
Friday, Apr 11, 2014 10:04 PM PDT
A drug being developed by Intercept Pharmaceuticals Inc led to significant improvement in signs of a rare liver disease that primarily affects middle-aged women, likely reducing the risk of need for liver transplant and of death, according to results of a late-stage clinical trial presented on Saturday. Nearly half the patients suffering from primary biliary cirrhosis who received the drug, obeticholic acid, achieved the primary goals of the study, compared with 10 percent for those who received a placebo, researchers said. The composite main goal of the study was to achieve at least a 15 percent reduction in levels of alkaline phosphatase, a biomarker for severity of the liver disease, serum alkaline phosphatase activity of less than 1.67 times the upper limit of normal and bilirubin within normal limits. "Reduction in alkaline phosphatase is really the best prognostic factor for survival," Dr. Frederik Nevens, the study's lead investigator and chairman of the department of hepatology at the University of Leuven, in Belgium, said in a telephone interview.
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